Skin1004 Madagascar Ampoule
SKIN1004's Madagascar Centella ampoule collection spans 21+ products across five distinct ampoule lines: the original Madagascar Centella Ampoule (in 55 ml and 100 ml), the Poremizing Fresh Ampoule for oily skin, the Hyalu-Cica First Ampoule for hydration layering, the Probio-Cica Intensive Ampoule for barrier repair, and the Tea-Trica Relief Ampoule for active breakouts. Each uses Madagascar-sourced centella as the primary extract with a different secondary profile. The Ampoule Foam rounds out the range as the cleansing step for the same ingredient system.
By Skinsli editorial Updated
Buying guide
SKIN1004 Madagascar Ampoule Lines: A Comparison Guide
SKIN1004 has expanded their flagship Madagascar Centella Ampoule into five distinct formulations, each pairing the centella extract base with a different secondary active. Choosing between them is a matter of identifying your skin's primary concern beyond calming - sebum, hydration, barrier repair, or active breakouts. This guide covers each ampoule line and its best-fit use cases.
The original Madagascar Centella Ampoule (55ml and 100ml)
The original Madagascar Centella Ampoule is the reference product for the entire line. It contains a near-100% concentration of centella asiatica leaf extract as the first ingredient - unusually high for a mass-market skincare product - with minimal supporting ingredients. It applies as a thin, watery concentrate over the toner step and absorbs quickly.
The 55 ml is the standard retail size, finishing in roughly 2-3 months with daily use (3-4 drops per session). The 100 ml is the professional size with better cost-per-ml for year-round users. Most dermatologists and estheticians who recommend SKIN1004 specify the original ampoule by default; the variant lines are refinements for specific concerns, not improvements on the base formula.
Poremizing Fresh Ampoule: for oily and combination skin
The Madagascar Centella Poremizing Fresh Ampoule (available in 50 ml and 100 ml) adds sebum-control and pore-tightening actives to the centella base. "Fresh" signals a lighter, gel-like texture compared to the original ampoule. This version is suited to oily and combination skin that finds the original ampoule slightly too film-forming in warm or humid conditions.
The Poremizing Fresh Ampoule pairs naturally with the Poremizing Light Gel Cream from the same sub-line. If pores and shine are your primary concern alongside calming, building a full Poremizing routine (toner → ampoule → gel cream) delivers the most consistent results.
Hyalu-Cica First Ampoule: centella plus hyaluronic acid
The Madagascar Centella Hyalu-Cica First Ampoule (50 ml and 100 ml) layers hyaluronic acid alongside the centella extract. "First" refers to its placement in the routine - it is designed as the first treatment step after cleansing, before the standard ampoule, acting as a plumping hydration base. The hyaluronic acid draws moisture into the upper dermis, which the centella then works on as a stabilizing ingredient.
This ampoule is the right pick for normal-to-dry skin that wants barrier calming and visible plumping simultaneously. It can also be used as the sole ampoule step on low-stress days when the full centella concentrate is unnecessary. In winter routines for dry climates, the Hyalu-Cica First Ampoule as a base layer before the original ampoule provides more moisture density than either alone.
Probio-Cica Intensive Ampoule: for barrier repair
The Madagascar Centella Probio-Cica Intensive Ampoule (50 ml and 95 ml) adds probiotic lysate to the centella base. Probiotic lysate - the fermented by-product of live bacterial cultures - has documented evidence for supporting the skin's acid mantle and microbiome balance. Combined with centella's anti-inflammatory action, this ampoule addresses chronic barrier disruption from two angles simultaneously.
It is the recommended option for post-active-acne recovery, eczema-adjacent skin, and post-procedure use (post-laser, post-peel) where the barrier microbiome is disrupted in addition to visible inflammation. The 95 ml and 50 ml sizes reflect that this tends to be a daily treatment choice rather than an occasional one.
Tea-Trica Relief Ampoule: centella plus tea tree
The Madagascar Centella Tea-Trica Relief Ampoule (100 ml) adds tea tree to the centella base for a mild antibacterial action at the ampoule step. "Tea-Trica" is SKIN1004's name for the tea tree + centella combination. This is the ampoule for actively breaking-out skin where bacteria are a contributing factor - not just redness from barrier damage.
SKIN1004 keeps the tea tree concentration low enough to avoid the irritation of undiluted tea tree applications; the centella base counterbalances the drying effect. It works well as an evening ampoule during active breakout phases, with the original ampoule used on calmer days. Some users use both - original in the morning, Tea-Trica in the evening - during a breakout cycle.
Ampoule Foam: extending centella to the cleanse step
The Madagascar Centella Ampoule Foam (125 ml) brings the Madagascar centella extract into the cleanser. It uses amino acid surfactants (glutamate-based) instead of sulfates, which maintain the skin's acid mantle better than SLS or SLES foams. It lathers moderately - enough to remove daily SPF and light sebum - and rinses without the tight post-cleanse feeling that drying surfactants cause.
The Ampoule Foam is the recommended cleanse step for anyone building a full Madagascar Centella routine. It is not a serum and does not replace the ampoule treatment step - it simply means the calming centella ingredient is present throughout the routine from cleanse to moisturizer.
50ml vs 100ml - choosing the right size
Most ampoule lines in this collection come in two sizes. The 50-55 ml sizes are suitable for first-time buyers who want to test the formula before committing to a larger volume. They typically last 6-10 weeks with daily use. The 100 ml sizes offer meaningfully better cost-per-ml for users who have confirmed the formula works for them.
The original Ampoule at 55 ml is slightly larger than the typical travel size, so it is a reasonable choice for a trial period. The 100 ml original ampoule is the standard professional size and is more economical for year-round users.
Where the ampoule sits in a routine
All Madagascar Centella ampoules apply after the toner step and before the moisturizer in both morning and evening routines. The Hyalu-Cica First Ampoule is the exception - it goes first among ampoules when stacking multiple treatment steps, with the original or variant ampoule applied on top.
Morning: Ampoule Foam → Toning Toner → Ampoule → (any serum) → Cream → SPF. Evening: Ampoule Foam → Toning Toner → Ampoule → Cream. On active nights, the ampoule layers over or under a retinol or acid depending on your buffering preference. Most SKIN1004 users apply ampoule under retinol as a barrier prep.
FAQ
Frequently asked questions
FAQ
Frequently asked questions
How concentrated is the Madagascar Centella Ampoule compared to a regular serum?
The original Madagascar Centella Ampoule lists centella asiatica leaf extract as the first ingredient - which means it is present at the highest proportion in the formula. Most serums that advertise centella use it as a secondary or tertiary ingredient at lower concentrations. SKIN1004's approach of leading with centella rather than water or glycerin is what distinguishes the ampoule from typical calming serums on the market.
Which Madagascar Centella ampoule is best for active breakouts?
The Tea-Trica Relief Ampoule (centella + tea tree) is the most targeted option for active breakouts with a bacterial component. The Probio-Cica Intensive Ampoule is better for the recovery phase after the breakout - when the lesion has cleared but the barrier is still disrupted. The original ampoule is suitable for redness and inflammation at any stage. Many acne-prone users rotate between Tea-Trica during flares and the original on calmer days.
Can I use the Hyalu-Cica First Ampoule together with the original Madagascar Centella Ampoule?
Yes - and this is the intended use for the Hyalu-Cica line. Apply the Hyalu-Cica First Ampoule as the first treatment step after toner, then layer the original ampoule on top. The hyaluronic acid in the First Ampoule draws moisture into the skin before the centella concentrate seals and calms. The combination is more hydrating than either alone and is practical for dry skin in winter.
What does the Probio-Cica Intensive Ampoule do that the original ampoule does not?
The Probio-Cica Intensive Ampoule adds probiotic lysate to the centella base. The lysate supports the skin's acid mantle and microbiome balance at the bacterial community level - an action the original centella extract does not address directly. For most healthy skin, the original ampoule is sufficient. For chronically disrupted skin (eczema-adjacent, post-antibiotic, or post-aggressive-peel), the microbiome support from the Probio-Cica makes a meaningful difference.
Can the Madagascar Centella Ampoule Foam replace the ampoule treatment step?
No - the Ampoule Foam is a cleanser. It removes sebum, SPF, and surface debris using amino acid surfactants and rinses off. The centella benefit from the Foam is limited to what remains on the skin during rinsing, which is minimal. The Ampoule Foam extends the centella story into the cleanse step, but the treatment ampoule (original or any variant) is still needed as a leave-on step afterward for the full concentration benefit.
Should I buy the 50ml or 100ml Hyalu-Cica First Ampoule for a first purchase?
The 50 ml is the sensible starting size for a first purchase - it provides 6-8 weeks of daily use and is enough to evaluate how the formula interacts with your skin before committing to the larger size. The 100 ml offers better cost-per-ml and is practical once you have confirmed the product works for you. This logic applies across all the ampoule variants in the collection.
Is the Poremizing Fresh Ampoule better than the original ampoule for humid summer months?
For oily and combination skin in warm weather, yes - the Poremizing Fresh Ampoule's lighter, gel-adjacent texture is less likely to contribute to shine than the original ampoule. It also includes sebum-control actives that are particularly useful in humidity. Dry and normal skin types usually do not notice a difference between the two in summer, but the Fresh version is worth switching to if the original feels heavy between June and August.
Are all SKIN1004 Madagascar Centella ampoules fragrance-free?
Yes. All ampoule products in the Madagascar Centella collection are free of added fragrance (parfum), essential oils, and colorants. This is a brand-wide policy for the Madagascar Centella line. The mild earthy or slightly herbal note some users detect is from the centella extract itself, not from added fragrance compounds. Fragrance-sensitive individuals can use the full range without that concern.
How often should I use the Tea-Trica Relief Ampoule versus the original ampoule?
The Tea-Trica Relief Ampoule is suitable for daily use, but many users treat it as a cycle-based product - using it during active breakout phases (typically 1-3 weeks) and then returning to the original ampoule on clearer days. Daily use is fine for consistently acne-prone skin; rotating prevents overuse of the tea tree component, which can cause mild sensitivity in some skin types over very long periods.








































