SKIN1004 Ampoules
SKIN1004's ampoule collection covers 21+ Madagascar Centella ampoule products organized by concern: the core Madagascar Centella Ampoule (55 ml and 100 ml), the Poremizing Fresh Ampoule (50 ml and 100 ml, for pore care), the Hyalu-Cica First Ampoule (50 ml and 100 ml, hyaluronic acid plus Centella), the Probio-Cica Intensive Ampoule (50 ml and 95 ml, probiotic formula), and the Tea-Trica Relief Ampoule (100 ml, for acne and redness). Plus the Ampoule Foam cleanser. All are built on Madagascar Centella asiatica as the primary soothing active.
By Skinsli editorial Updated
Buying guide
SKIN1004 Ampoule Buying Guide: All Centella Ampoule Variants Explained
SKIN1004's ampoule lineup is the deepest part of the brand's Madagascar Centella range. With 21+ products covering five distinct ampoule types - each targeting a different skin concern - plus the Ampoule Foam cleanser, the collection requires some navigation. This guide explains each ampoule variant's purpose and which skin types it suits best.
What an ampoule is and how it differs from a serum or essence
Ampoules are concentrated treatment products with a higher active ingredient load than standard serums or essences, typically used as a targeted treatment layer rather than an everyday moisturizing product. In the SKIN1004 range, ampoules serve as the focused delivery mechanism for Madagascar Centella and whatever secondary active (hyaluronic acid, probiotic ferment, tea tree complex) defines each variant's specific concern.
In a routine, ampoules are applied after toning or essence and before heavier serums or cream - the lightest to heaviest sequencing standard in Korean skincare. Some SKIN1004 ampoules are sold as "first ampoules" (like the Hyalu-Cica First Ampoule), meaning they're designed to be the very first step after cleansing - lighter than even a standard essence.
Madagascar Centella Ampoule 55 ml and 100 ml: the foundational formula
The Madagascar Centella Ampoule is the core product in the ampoule lineup - a concentrated Centella extract ampoule focused on soothing, calming, and barrier repair. It contains a high concentration of Madagascar Centella asiatica leaf extract, delivering asiaticosides and madecassoside directly to the skin surface for rapid anti-inflammatory action.
It's available in 55 ml and 100 ml. The 100 ml is the better-value daily use size; the 55 ml is appropriate for travel or for a first test before committing to the larger bottle. The formula is lightweight and watery, absorbing quickly, and it can be used on the full face or as a spot application on areas of redness or irritation. It suits all skin types but is most valuable for sensitive, reactive, and redness-prone skin.
Poremizing Fresh Ampoule 50 ml and 100 ml: centella plus pore-minimizing action
The Poremizing Fresh Ampoule combines Madagascar Centella with pore-focused actives - BHA (beta-hydroxy acid, typically salicylic acid) at a mild concentration and sebum-controlling ingredients. The "fresh" texture is noticeably lighter and more fluid than the core Centella Ampoule, making it well-suited to oily and combination skin that needs the Centella anti-inflammatory benefit without added weight.
The BHA component provides gentle chemical exfoliation inside pores, keeping them clear of the debris and sebum that cause enlarged pore appearance. At 50 ml and 100 ml, the Poremizing Fresh Ampoule is available in both sizes. The 100 ml is the economical choice for daily users. For acne-prone skin specifically, the Tea-Trica Relief Ampoule is more targeted at active breakouts; the Poremizing Fresh Ampoule is better for general pore maintenance and oiliness control.
Hyalu-Cica First Ampoule 50 ml and 100 ml: centella plus hyaluronic acid
The Hyalu-Cica First Ampoule is designed as the very first step after cleansing - before toner, before serum - making it a unique position in the routine compared to the other ampoules. "Hyalu" refers to hyaluronic acid, added here to provide immediate moisture-binding on freshly cleansed skin. The combination of hyaluronic acid and Centella creates a two-action first step: plump the skin with moisture while beginning the centella soothing and barrier-preparation process.
Applied on slightly damp skin immediately after cleansing, the Hyalu-Cica First Ampoule delivers the most benefit when the skin surface is still hydrated and the pores are at their most receptive. It's available in 50 ml and 100 ml. This product is particularly beneficial in dry climates or during seasons when skin loses moisture quickly after washing - the immediate hyaluronic acid layer counters that water loss before it can occur.
Probio-Cica Intensive Ampoule 50 ml and 95 ml: microbiome-targeted treatment
The Probio-Cica Intensive Ampoule is the most sophisticated formula in the SKIN1004 ampoule range. It combines Madagascar Centella with probiotic-derived ferment ingredients that support the skin's microbiome diversity and function. "Intensive" signals a higher active concentration than the standard Centella Ampoule - this product is for skin that needs a deeper treatment intervention.
Probiotic-ferment ingredients in skincare support the beneficial bacteria on the skin surface that contribute to barrier function and immune response. When the skin microbiome is disrupted - by antibiotics, over-cleansing, or harsh treatments - the barrier weakens and sensitivity increases. The Probio-Cica Ampoule addresses this at a microbial level alongside the Centella's anti-inflammatory action. It's available in 50 ml and 95 ml. For mature, compromised, or chronically sensitive skin, it's the most comprehensive treatment ampoule in this collection.
Tea-Trica Relief Ampoule 100 ml: for active acne and redness
The Tea-Trica Relief Ampoule targets active acne and the redness it causes. It combines tea tree oil (antimicrobial, anti-acne) with SKIN1004's Trica-cica complex - a three-component calming complex - and Madagascar Centella for anti-inflammatory support. The combination addresses both the microbial cause of acne (tea tree) and the inflammatory response it triggers (Centella and Trica-cica).
Unlike the Poremizing Fresh Ampoule, which focuses on pore size and sebum control, the Tea-Trica Relief Ampoule is most beneficial during active breakout periods - when pimples are inflamed and red. It can be applied over the full face for oily and acne-prone skin, or used as a targeted application on individual spots. At 100 ml, it's a single-size format for this variant in the current collection.
How to pick the right SKIN1004 ampoule for your primary skin concern
Quick-reference by primary concern: General soothing, redness, and sensitivity - Madagascar Centella Ampoule. Enlarged pores and oiliness - Poremizing Fresh Ampoule. Dehydration and first-step moisture - Hyalu-Cica First Ampoule (applied before toner). Disrupted microbiome, chronic sensitivity, or post-procedure skin - Probio-Cica Intensive Ampoule. Active acne and inflamed breakouts - Tea-Trica Relief Ampoule.
For beginners to the SKIN1004 ampoule range, the core Madagascar Centella Ampoule in 55 ml is the most broadly beneficial and the natural starting point before exploring the targeted variants. Once the core formula's benefits are familiar, adding a second ampoule for a specific concern is the next step.
Madagascar Centella Ampoule Foam 125 ml: Centella care starting at the cleanse step
The Ampoule Foam is SKIN1004's centella-infused cleansing foam - it's a cleanser, not a treatment ampoule, but it's included in this collection because it initiates Centella contact from the very first step of the routine. The formula is a gentle foaming cleanser suitable for daily use; the Centella extract in it provides a mild pre-treatment contact during the 30 to 60 seconds of massage on the face before rinsing.
For a fully unified SKIN1004 Centella routine - Ampoule Foam to cleanse, then the core Centella Ampoule or targeted variant as the treatment ampoule - the Ampoule Foam is the natural cleanser complement. It's available at 125 ml, which at twice-daily face washing lasts approximately 2 to 3 months.
FAQ
Frequently asked questions
FAQ
Frequently asked questions
Should I use the Madagascar Centella Ampoule or the Hyalu-Cica First Ampoule if I have dry and sensitive skin?
Use the Hyalu-Cica First Ampoule as the very first step after cleansing, then follow with the core Centella Ampoule at the next layer if you want double centella coverage - or use the Hyalu-Cica First Ampoule alone if simplicity is the goal. For dry and sensitive skin, the Hyalu-Cica First Ampoule is the better entry product because its immediate hyaluronic acid delivery prevents water loss on freshly cleansed skin, and the centella component starts soothing simultaneously.
Does the SKIN1004 Poremizing Fresh Ampoule contain salicylic acid (BHA)?
The Poremizing Fresh Ampoule includes BHA-type actives for pore-clearing action - SKIN1004 uses a gentle concentration appropriate for daily use rather than a clinical exfoliant level. The BHA works inside the pores to keep them clear of sebum and debris, which over time reduces the visual appearance of enlarged pores. It's milder than dedicated BHA exfoliant products, making it suitable for daily use without the irritation risk of high-percentage BHA treatments.
Can the Probio-Cica Intensive Ampoule help restore skin balance after a course of oral antibiotics?
The Probio-Cica Intensive Ampoule is relevant for this situation. Oral antibiotics disrupt the gut and skin microbiomes, and post-antibiotic skin often shows increased sensitivity, redness, or breakouts as the balanced microflora is temporarily reduced. The probiotic-ferment ingredients in the Probio-Cica Ampoule support the beneficial microorganisms on the skin surface, and the Centella addresses the inflammation associated with microbiome disruption. It won't repair the gut microbiome, but for the skin surface specifically, it's a well-targeted support product.
For oily, acne-prone skin, should I choose the Tea-Trica Relief Ampoule or the Poremizing Fresh Ampoule?
Use Tea-Trica Relief Ampoule during active breakout periods - when pimples are inflamed and active. Use the Poremizing Fresh Ampoule for ongoing pore maintenance and oil control during periods when the skin is mostly clear. The two can also be alternated: Tea-Trica when acne-active, Poremizing when maintaining. Many people with oily, acne-prone skin use the Poremizing Ampoule as their daily product and switch to Tea-Trica during breakout flares.
How long does the SKIN1004 Madagascar Centella Ampoule 100 ml last?
At 3 to 5 drops per application once daily on the full face, the 100 ml bottle lasts approximately 3 to 4 months. At twice-daily use, closer to 6 to 8 weeks. The 55 ml provides roughly half the supply - approximately 6 to 8 weeks at once-daily use. The 100 ml is the better-value ongoing purchase for daily users; the 55 ml suits travel or first-time buyers.
Is the Hyalu-Cica First Ampoule suitable for oily skin?
Yes. The Hyalu-Cica First Ampoule is a lightweight, watery formula without oils or heavy emollients - it's well-suited for oily skin. Hyaluronic acid is a water-binding humectant, not an oil, so it doesn't add oiliness. For oily skin, apply the Hyalu-Cica First Ampoule immediately after cleansing on damp skin, then follow with the Poremizing Fresh Ampoule if pore control is also a priority.
Is the Madagascar Centella Ampoule Foam suitable for daily twice-a-day cleansing?
Yes. The Ampoule Foam is formulated for gentle daily cleansing - it's appropriate for both morning and evening use. The formula produces a mild lather that cleanses effectively without stripping, making it suitable for sensitive and barrier-compromised skin. For heavy makeup or sunscreen removal in the evening, a double cleanse (oil or balm cleanser first, then Ampoule Foam as the second cleanse) gives a more thorough result than the foam alone.
Is there a formula difference between the Probio-Cica Intensive Ampoule 50 ml and 95 ml?
No formula difference - both sizes contain the same Probio-Cica Intensive Ampoule formula. The 95 ml is the larger-volume format at lower cost per ml; the 50 ml suits first-time buyers or travel. For daily users who have confirmed the formula suits their skin, the 95 ml is the more economical ongoing purchase.
Are the SKIN1004 ampoules on skinsli.com genuine Korean imports?
Yes. All SKIN1004 Madagascar Centella ampoules are genuine Korean imports in original packaging. SKIN1004 is a Korean brand and these products are the same items sold in Korean beauty stores and dermatology clinics. They are not repackaged, reformulated, or grey-market goods.