SCINIC Ampoules
SCINIC Ampoules brings together 23+ concentrated serum-step products across four ingredient families. The Sicanoid/Shikanoid Ampoule (50ml and 100ml) is built around SCINIC's proprietary Sicanoid complex. The First Concentrate Ampoule is a multi-ingredient treatment available in full size and 1ml sample. The Collagen Ampoule Stick (10g, available in current and legacy versions) delivers collagen in a solid stick format. The Hyaluronic Acid Ampoule Serum (50ml) and Ampoule Skin (150ml, 300ml) carry the HA-focused lines. All products are designed as intensive treatment steps after toner.
By Skinsli editorial Updated
Buying guide
SCINIC Ampoules: A Guide to Every Concentrated Treatment in the Range
Ampoules are high-concentration treatment products applied between toner and moisturizer in a Korean skincare routine. SCINIC's 23+ ampoule products cover four distinct ingredient families: the Sicanoid/Shikanoid proprietary complex, the First Concentrate multi-benefit formula, Collagen in a stick format, and Hyaluronic Acid in both serum and toner-weight variants. This guide explains each product, what it targets, and how to choose between them.
What an Ampoule Is in Korean Skincare
In Korean skincare, an ampoule is a concentrated serum or essence with a higher active ingredient load than a standard serum or toner. The term comes from the pharmaceutical ampoule (a sealed glass vial of concentrated compound), and the skincare format carries the same idea: maximum active delivery in a small volume. Ampoules are applied after toner and essence, before moisturizer, as the intensive treatment step.
SCINIC uses "ampoule" across both toner-weight products (Hyaluronic Acid Ampoule Skin) and serum-weight products (Hyaluronic Acid Ampoule Serum, Sicanoid Ampoule). The toner-weight ampoule skins are first-step products; the serum-weight ampoules and sticks are the treatment step. Reading the product name and format clarifies where in the routine each one goes.
Sicanoid/Shikanoid Ampoule: 50ml and 100ml
The Sicanoid Ampoule (also rendered as Shikanoid in some product titles) is SCINIC's proprietary complex ampoule in two sizes: 50ml and 100ml. The Sicanoid complex is SCINIC's branded active ingredient system, which based on the product positioning addresses multiple skin concerns in a single formula rather than focusing on one ingredient category. At 50ml and 100ml, these are larger volumes than typical single-ingredient ampoules (usually 15-30ml), suggesting they are intended for daily use as a primary ampoule step rather than intermittent targeted treatment.
The 100ml size is the largest volume option in the SCINIC ampoule range and is a strong value choice for daily users who have confirmed the Sicanoid formula works well for their skin. The 50ml is the right entry point for first-time buyers of the Sicanoid line.
First Concentrate Ampoule
The First Concentrate Ampoule is a multi-benefit treatment ampoule available in full size and in a 1ml single-use sample. "First Concentrate" is a category term in Korean skincare that refers to a multi-function high-concentration first ampoule - a product meant to go in very early in the routine (sometimes before toner) and address multiple concerns simultaneously rather than targeting one specific ingredient.
The 1ml sample is one of the more unusual formats in the SCINIC range and is useful for testing the formula before committing to a full size, or for travel. If the First Concentrate Ampoule matches your skin well from the 1ml trial, it is a practical step to add to your routine before your regular toner or serum.
Collagen Ampoule Stick 10g
The Collagen Ampoule Stick (10g) is a solid-format ampoule that delivers collagen in a balm-stick format. Solid ampoule sticks are a product category distinctive to Korean skincare - they are applied by pressing the stick directly onto specific areas of the face (around the eyes, nasolabial folds, forehead lines) or swiped broadly before patting in with fingertips. The stick format provides more targeted application than a liquid dropped onto the whole face.
Collagen in topical products is associated with plumping and temporary line reduction. The 10g stick format and the collagen active make this product particularly useful as a spot treatment for areas where fine line or volume loss is the focus. The "old" (legacy) and "NEW" current versions may differ in formula; the NEW version is the current formulation in the range.
HA Ampoule Serum vs HA Ampoule Skin: Which One Goes First
Both the Hyaluronic Acid Ampoule Serum (50ml) and the Hyaluronic Acid Ampoule Skin (150ml, 300ml) are in the ampoule range but serve different routine positions. The Ampoule Skin is a toner-weight first-step product - apply after cleansing. The Ampoule Serum is thicker and more viscous, applied after the Ampoule Skin and before moisturizer. This is a common source of confusion when first building a SCINIC HA routine.
If you only buy one: the Ampoule Skin is the higher-volume, lower-cost-per-use option and is effective as a standalone step. The Ampoule Serum adds a more concentrated, film-forming serum layer for users who want deeper hydration delivery than the Ampoule Skin alone provides.
Choosing the Right Ampoule for Your Concern
Match your primary concern to the ampoule ingredient: Hyaluronic Acid Ampoule Serum for dehydration, Collagen Ampoule Stick for targeted fine lines and plumping, Sicanoid Ampoule for a multi-benefit daily treatment step, First Concentrate Ampoule for a broad-spectrum first-step intensive treatment. Most users run one primary ampoule daily and add a second targeted product (like the Collagen Stick) for specific zones.
A layering sequence for multiple SCINIC ampoules: after cleansing, First Concentrate (if using) → Hyaluronic Acid Ampoule Skin (toner) → Hyaluronic Acid Ampoule Serum → Sicanoid Ampoule → Collagen Stick (spot treatment) → moisturizer. In practice, few users run all five steps daily. Pick one to two primary ampoule products and use them consistently rather than cycling through five products inconsistently.
Sample and Travel Sizes in the Ampoule Range
The First Concentrate Ampoule 1ml sample and the Collagen Ampoule Stick at 10g are the two smallest formats in the range. The 1ml sample is a true trial size for the First Concentrate, useful before buying a full-size bottle. The Collagen Stick at 10g is not a trial size but a full-use compact format by design - the 10g weight is the standard size for this product. Both fit easily in travel bags within international liquid carry-on limits.
For travelers who want a full ampoule routine on the road, the Collagen Stick (10g, solid, no liquid restrictions) and the Hyaluronic Acid Ampoule Serum decanted into a 15-30ml travel bottle cover the primary ampoule steps within airline restrictions.
FAQ
Frequently asked questions
FAQ
Frequently asked questions
Is the SCINIC Sicanoid Ampoule the same product as the Shikanoid Ampoule?
Yes. Sicanoid and Shikanoid are transliteration variants of the same SCINIC proprietary complex name in Korean. The product titles differ because Korean-to-English transliteration is not standardized, and different importers or packaging versions use slightly different romanizations. Both the 50ml and 100ml versions in this collection refer to the same Sicanoid complex ampoule. When ordering, confirm the volume you want from the product listing rather than relying solely on the name transliteration.
How do I apply the SCINIC Collagen Ampoule Stick 10g?
Apply the stick after your toner or ampoule skin step, before your moisturizer. Push up the stick slightly from the base and press it directly onto the skin along areas of concern - under the eyes, along the nasolabial folds, on the forehead, or across the full face in gentle strokes. Then pat the product into the skin with your fingertips until absorbed. Unlike a liquid ampoule, the stick format gives you precise placement without dripping. The NEW version is the current formula; the old version is a legacy batch available while stocks last.
Is the First Concentrate Ampoule 1ml sufficient to test the product before buying full size?
The 1ml sample gives you one to two full-face applications at a standard serum drop amount, which is enough to check for immediate skin reactions (stinging, redness, breakouts) and to get a sense of texture and absorption. For a full skin-tolerance evaluation, 3-7 days of consistent use is more reliable than a single application. If one trial is fine, consider buying the smallest full-size available before committing to a large bottle.
If I have both the SCINIC HA Ampoule Skin 300ml and the HA Ampoule Serum 50ml, which goes first?
Apply the Ampoule Skin first - it is the toner-weight product and goes immediately after cleansing. Then apply the Ampoule Serum as the treatment serum step. The rule is thin to thick: the Ampoule Skin is a watery first essence, the Ampoule Serum is a thicker, film-forming serum. Reverse order would mean a heavier layer blocking absorption of the lighter one. After the Ampoule Serum, apply moisturizer (lotion or cream) as the final sealing step.
Can I use the SCINIC Sicanoid Ampoule 100ml every day, or is it an intensive treatment?
The 100ml size suggests the Sicanoid Ampoule is designed for daily use rather than intermittent intensive application. At daily use (3-5 drops twice daily), the 100ml provides approximately 4-6 months of supply. Apply after your toner step and before moisturizer. The large volume is one of the indicators that SCINIC positions this as a regular routine product rather than a periodic treatment ampoule used a few times a week.
Can I use both the SCINIC Collagen Ampoule Stick and the Hyaluronic Acid Ampoule Serum in the same routine?
Yes. Apply the Hyaluronic Acid Ampoule Serum first as the serum step, let it absorb for 30-60 seconds, then apply the Collagen Stick as a targeted second step on specific areas. Collagen and hyaluronic acid address different mechanisms - HA pulls water to the surface; topical collagen supports plumping and temporary film-forming at the skin surface - so they are complementary rather than redundant. This is a practical combination for users whose concerns include both dehydration and visible fine lines.
Are SCINIC ampoule products on skinsli authentic Korean imports?
Yes. SCINIC products on skinsli are sourced through Korean distribution channels. Korean-language labeling on the packaging confirms authenticity. The formulations are the same as the Korean domestic versions.















