isoi Ampoules

The ISOI ampoule collection spans 11+ concentrated treatment products across several sub-lines. The Moisture Doctor range provides hydration-repair ampoules (40ml standard and Speedy Cream variant). The Bulgarian Rose line offers the Ultra Water Pool Ampoule 15ml and Moisture ZIP Cream Ampoule 70ml. The Intensive line covers the Lifting Ampoule Stick 15ml and the Anti-aging Program Elastic Ampoule 30ml. Additional formats include the Compression Cream Ampoule 70ml and the Chicago Sika Double Effect Ampoule 30ml.

  • Hydration and lifting options
  • Bulgarian rose variants
  • Multiple size formats
  • Korean formulation

By Skinsli editorial Updated

Buying guide

Buying Guide: ISOI Ampoule Collection

The ISOI ampoule collection brings together concentrated treatment products from several of the brand's sub-lines. Unlike standard serums, these ampoules deliver a high active concentration in a smaller per-session quantity, applied between toner and moisturiser. The collection spans hydration-repair (Moisture Doctor), anti-aging and lifting (Intensive), Bulgarian rose actives (Ultra Water Pool Ampoule, Moisture ZIP Cream Ampoule), and multi-effect formats (Chicago Sika Double Effect, Compression Cream Ampoule). This guide explains each product and how to choose between them.

Ampoule Formats in the ISOI Collection

The ISOI ampoule range covers three format types. Liquid serums (Moisture Doctor Ampoule 40ml, Chicago Sika Double Effect Ampoule 30ml, Intensive Elastic Ampoule 30ml, Ultra Water Pool Ampoule 15ml) are the most standard format - applied in drops after toner. Cream-ampoule hybrids (Compression Cream Ampoule 70ml, Moisture Doctor Speedy Cream Ampoule 40ml, Moisture ZIP Cream Ampoule 70ml) combine ampoule-level actives with a cream texture, functioning as a moisture step with concentrated treatment properties. The Intensive Lifting Ampoule Stick 15ml is an ergonomic stick applicator for targeted contour application.

The format differences affect where in the routine each product sits. Liquid ampoules apply at the serum step; cream ampoules can replace or supplement the moisturiser step.

Moisture Doctor Ampoule and Speedy Cream Ampoule

Two Moisture Doctor ampoules appear in the collection. The Moisture Doctor Ampoule 40ml (also listed as Moisture Doctor Ampoule Moisture Ampoule 40ml - the same product) is a liquid serum applying at the treatment step after the Moisture Doctor Toner. At 40ml it is larger than most ampoules, reflecting its role as a daily step rather than a short-course intensive. The Moisture Doctor Speedy Cream Ampoule 40ml is the cream-ampoule variant, absorbing quickly and providing both treatment and moisture in one layer.

Choose the standard Ampoule 40ml for dry skin needing a dedicated serum layer before a separate moisturiser. Choose the Speedy Cream Ampoule for oily or combination skin where a combined serum-plus-light-moisture step reduces the total number of layers without sacrificing the Moisture Doctor actives.

Compression Cream Ampoule 70ml

The Compression Cream Ampoule 70ml is the largest product in the collection - a cream-ampoule format combining treatment-level active concentration with a full daily moisturiser size. The Compression designation suggests a formula that helps the skin maintain its structure and moisture retention through a tightening or barrier-compression approach. At 70ml it is generous for daily use, covering approximately two to three months as a routine moisturiser.

This product suits skin that needs both treatment and solid daily moisture in one step, eliminating the need for a separate serum and cream when the concentrated cream format provides both. It is heavier than the Speedy Cream Ampoule and more appropriate for dry or mature skin than for oily skin types.

Ultra Water Pool Ampoule 15ml and Bulgarian Rose Version

The Ultra Water Pool Ampoule 15ml and its Bulgarian Rose variant (Bulgarian Rose Ultra Water Pool Ampoule 15ml) are compact 15ml ampoules providing intensive hydration in a water-type formula. The Water Pool designation suggests a formula with a high water-binding capacity, delivering a burst of hydration at the serum step. The Bulgarian Rose version adds rose extract's calming and antioxidant properties to the same hydration base.

At 15ml both are small ampoules suited for trial, travel, or as a supplementary booster layered before a primary serum. They are not primary daily treatment products at this size - they provide an additional hydration layer within a broader routine rather than serving as the main serum step.

Intensive Lifting Ampoule Stick 15ml

The Intensive Lifting Ampoule Stick 15ml is the most distinctively formatted product in the collection. The stick applicator - either a rollerball or pointed tip - delivers lifting ampoule actives precisely along contour areas: jawline, cheekbones, and the outer eye area. This format applies the product with a massaging motion that complements the lifting intent of the formula, since the mechanical stimulation from rolling also improves circulation and product absorption.

Use the Ampoule Stick at the serum step, tracing it along contour areas before the face cream. It works well as a secondary step alongside the standard Intensive Lifting Serum from the ISOI Intensive range, or as a standalone lifting treatment in a minimal routine that doesn't need a full-face serum.

Chicago Sika Double Effect Ampoule 30ml

The Chicago Sika Double Effect Ampoule 30ml is from the ISOI Chicago sub-line with a sika (deer) placenta or sika-named complex as a key active. Double Effect products in Korean skincare typically combine two complementary functions in one formula - in this case, likely brightening and hydration or anti-aging and moisture. At 30ml it is a standard ampoule size for approximately three to four weeks of daily use as the serum step.

The Chicago Sika Ampoule is positioned as a multi-function treatment targeting two concerns simultaneously. It is suited to skin that needs more than one type of active at the serum step without wanting to apply two separate serums.

Intensive Perfect Anti-aging Program Elastic Ampoule 30ml

The Intensive Perfect Anti-aging Program Elastic Ampoule 30ml belongs to the Intensive range and sits at the concentrated end of ISOI's anti-aging treatment options. The Elastic designation indicates a formula focused on skin elasticity - improving the skin's ability to spring back and resist the sagging associated with collagen and elastin decline. At 30ml it is a standard serum size for three to four weeks of daily use.

This ampoule pairs naturally with the Intensive Lifting Serum and Ampoule Stick from the broader Intensive collection - all three address different aspects of skin firmness and elasticity. Use the Elastic Ampoule at the main serum step and the Lifting Ampoule Stick as a targeted contour application at the same routine position or after the serum is absorbed.

FAQ

Frequently asked questions

  • ISOI ampoules are more concentrated than typical serums, applying in smaller quantities per session. They deliver a higher active load per drop and are formulated for a specific targeted concern rather than general skin maintenance. The Moisture Doctor Ampoule 40ml and the Intensive Elastic Ampoule 30ml both follow this logic - smaller amounts per use than a standard serum, but with a higher active concentration. Some ISOI ampoules are in cream format (the Compression Cream Ampoule 70ml, Speedy Cream Ampoule) which work more like a treatment moisturiser than a traditional thin-fluid serum.

  • The Moisture Doctor Ampoule is designed for daily use at the serum step, both morning and evening. Apply two to three drops after the Moisture Doctor Toner and before your moisturiser. At 40ml with twice-daily use, it provides approximately one month of supply. If you find the full two-drop morning application too much, use it once daily in the evening and combine with a lighter serum in the morning.

  • Yes. The Moisture Doctor Speedy Cream Ampoule combines the treatment actives of an ampoule with the moisture layer of a cream, eliminating the need for separate serum and moisturiser steps. Apply it after your toner as a one-step treatment-and-moisture finish. For dry skin, you may want to layer a second richer cream on top in the evening, as the Speedy Cream's lighter texture may not provide enough moisture sealing for severely dry skin overnight. For oily and combination skin, it is typically sufficient as a standalone final step.

  • The Lifting Ampoule Stick is best applied to areas showing visible firmness reduction: the jawline and jowl area, the lower cheek and nasolabial zone, and the crow's feet area at the outer eye. Trace the stick along the jawline from chin to ear, then along the lower cheekbone. Apply three to four passes per area. The rolling or tracing motion provides both active delivery and a light massaging stimulation that supports the lifting formula's intent.

  • Apply the Ultra Water Pool Ampoule after toner and before your primary serum, using three to four drops pressed into slightly damp skin. At 15ml it is a compact size best used as a booster layer rather than the main serum step. The Water Pool formula provides a concentrated hydration layer that enhances the absorption of subsequent actives. The Bulgarian Rose Ultra Water Pool Ampoule applies in the same way and adds rose extract calming at the same step.

  • The Elastic Ampoule targets skin elasticity - the skin's ability to spring back and resist the sagging associated with collagen and elastin decline. It is most relevant for mature skin showing visible laxity, reduced firmness at the jawline and cheeks, or skin that recovers slowly from pressure. The Anti-aging Program designation positions it as part of the Intensive range's systematic approach to aging concerns. Use it daily at the serum step alongside the Intensive Lifting Ampoule Stick for targeted contour application.

  • The Chicago Sika Double Effect Ampoule combines two complementary treatment functions in one formula. The Sika component refers to an active derived from or named after sika deer, which in Korean cosmetics is associated with regenerating and brightening properties. The Double Effect pairing typically addresses both brightening and moisture, or anti-aging and brightening simultaneously. The exact dual-effect pairing is confirmed on the product page ingredient and claim information. At 30ml it is a standard-sized ampoule for daily serum-step use over approximately three to four weeks.

  • Yes. The Compression Cream Ampoule 70ml is the largest and richest cream-ampoule in the collection, calibrated for dry and mature skin that needs both treatment actives and substantive daily moisture. At 70ml it lasts approximately two to three months as a daily moisturiser, making it one of the most economical-per-application products in the collection. Apply as the final routine step (before SPF in the morning). For very dry skin in cold weather, layer it under a separate facial oil or occlusive for maximum overnight moisture retention.

  • The Bulgarian Rose Moisture ZIP Cream Ampoule 70ml is the Bulgarian Rose version of a cream ampoule, adding rose extract to a moisture-ZIP (fast-sealing) formula. The Compression Cream Ampoule is from a different sub-line with a different base formula focused on structural support and barrier compression. Both are cream ampoules at 70ml, but they serve different primary concerns: the Moisture ZIP is a moisture-forward fast-absorb product suited to combination skin; the Compression Cream is more substantive for dry or mature skin needing structural moisture.