Anua Hyaluronic Capsule Serum

This collection is dedicated to the Anua PDRN Hyaluronic Acid Capsule 100 Serum and its associated formats: full-size serum, 30ml travel serum, 1ml single-use sample, and the Capsule 100 Serum Mask Sheet - 4 products total. The capsule format suspends micro-encapsulated hyaluronic acid in a serum base; the capsules burst on skin contact to release the HA payload directly. PDRN (polydeoxyribonucleotide) acts as a co-active to support barrier repair alongside the HA hydration.

  • Micro-capsule HA delivery
  • PDRN barrier support
  • Sample, travel and full size
  • Korean skincare

By Skinsli editorial Updated

Buying guide

Anua PDRN Hyaluronic Acid Capsule 100 Serum: All Formats Explained

The Anua PDRN Hyaluronic Acid Capsule 100 Serum is available in four formats on skinsli: full-size serum, 30ml travel serum, 1ml sample, and a Capsule 100 Serum Mask Sheet. All four deliver the same PDRN and micro-encapsulated hyaluronic acid formula, but at different use frequencies and application methods. This guide covers the capsule delivery mechanism, what PDRN contributes, and when to choose each of the four available formats.

The Micro-Encapsulation Delivery Mechanism

Micro-encapsulation in the PDRN HA Capsule 100 Serum works by surrounding hyaluronic acid molecules inside microscopic lipid shells. These shells are stable in the serum liquid but break open when they contact the friction and warmth of the skin surface, releasing the HA payload at the point of application. This differs from standard HA serums where the HA is dissolved directly in the water base and begins interacting with the skin surface as soon as the serum is applied. The encapsulation adds a slight gel-bead texture to the serum; the capsules are visible in the formula and the burst sensation is perceptible on application.

What PDRN Adds to the Capsule Serum Formula

PDRN (polydeoxyribonucleotide) is derived from salmon DNA and used in dermatological procedures for tissue repair and regeneration. In the Capsule 100 Serum, PDRN is present as a barrier-repairing co-active alongside the encapsulated HA. Its role is to support the skin's structural repair processes while the HA addresses surface hydration. This combination targets two aspects of compromised skin simultaneously: depleted surface moisture (addressed by HA) and underlying barrier weakness (addressed by PDRN). The result is a serum that is more complete for barrier-impaired skin than a standard single-active HA serum.

Full-Size PDRN HA Capsule 100 Serum for Daily Use

The full-size Anua PDRN Hyaluronic Acid Capsule 100 Serum is the most economical option for daily use. Applied after toner and before moisturizer, 2-3 drops is sufficient for a full-face application. Press the formula into the skin with clean palms rather than rubbing to preserve the capsule content during application. At a typical daily use rate, the full-size bottle provides approximately 2-3 months of use. Store away from direct sunlight; the capsule formula is more sensitive to heat than standard serums because elevated temperatures can destabilize the lipid shells before they reach the skin.

30ml Travel Size: Carry-On Compliant and Trial-Length

The PDRN Hyaluronic Acid Capsule 100 Serum in 30ml is both carry-on liquid limit compliant (under the 100ml threshold) and a practical trial size for new users. At daily use, 30ml provides approximately 4-6 weeks of applications. This is enough time to observe how the skin responds and whether the capsule serum delivers the hydration improvement you are looking for. The 30ml is also included in the PDRN Serum 30ml and Moisture Cream 30ml Set, which pairs the serum with its complementary moisturizer for a two-step trial.

1ml Single-Use Sample: Testing the Capsule Texture

The PDRN HA Capsule 100 Serum 1ml is a single-use sample size. It contains enough formula for one complete full-face application and is designed to let you test the capsule burst texture and verify your skin's tolerance before purchasing the 30ml or full-size. The 1ml format is also useful for sharing with someone who is considering whether to buy the serum. Apply the entire 1ml to freshly cleansed skin in the normal serum application step; the volume is calculated for one full-face use rather than a small patch-test application.

Capsule 100 Serum Mask Sheet for Intensive Treatments

The PDRN Hyaluronic Acid Capsule 100 Serum Mask Sheet uses the capsule serum formula as the soaking medium for a sheet mask. The occlusive mask sheet prevents evaporation during the treatment period, concentrating the PDRN and HA absorption compared to applying the serum freely with hands. The mask is intended for intensive hydration sessions rather than daily use: recovery after sun exposure, very dry weather, or as a pre-event treatment. Leave on for 15-20 minutes, then press the remaining formula into the skin with palms rather than rinsing. Using the mask sheet once or twice per week alongside the daily serum creates a two-tier hydration treatment structure.

Storage Conditions for the Capsule Serum

The micro-capsule format is more sensitive to temperature than conventional serums. Store the PDRN HA Capsule 100 Serum in a cool, dark location away from heat sources and direct sunlight. Avoid leaving it in a bathroom with high humidity and temperature fluctuation; a bedroom or dressing table in normal room conditions is appropriate. The 30ml and full-size bottles are sealed to protect from air exposure, but opening the bottle frequently in humid environments reduces shelf life. The 1ml sample should be used within a day of opening as the single-use format is not designed for repeated resealing.

Set Pairing: Capsule Serum 30ml with Moisture Cream 30ml

The PDRN HA Capsule 100 Serum 30ml and PDRN Hyaluronic Acid 100 Moisture Cream 30ml set is the most efficient entry point into the PDRN HA routine. The set gives you the core two-step combination (treatment serum + sealing cream) at trial sizes and at a better combined price than buying both products individually. Both products are from the same PDRN HA 100 series, so the formulas are designed to complement each other. The serum layer focuses on HA delivery via the capsule mechanism; the cream layer seals and adds emollient nourishment. This pairing covers the moisture treatment and the moisture lock in one purchase.

FAQ

Frequently asked questions

  • Yes. The micro-capsules appear as small spherical particles suspended in the serum liquid. When you shake or press the bottle, they are visible as slightly opaque beads distributed through the otherwise clear base. When applied to skin and pressed, you can feel a faint burst sensation as the capsules release their HA payload. If the serum appears uniformly liquid without visible particles, it may have been exposed to heat that destabilized the capsule shells.

  • The mask sheet is soaked in the same PDRN and encapsulated HA formula as the liquid Capsule 100 Serum. The difference is delivery format: the sheet mask holds a larger volume of the formula against the skin for 15-20 minutes with occlusion, while the liquid serum is applied in a thinner layer and absorbs freely. The mask sheet delivers a higher single-session concentration than the daily serum application but is not meant for daily use.

  • At a typical daily use volume of 2-3 drops of serum per application and a pea-sized amount of cream, the 30ml serum lasts approximately 4-6 weeks and the 30ml cream lasts a similar 4-6 weeks. The two products in the set are sized to run out at roughly the same time when used together daily as a serum-then-cream routine.

  • Heat above approximately 30-35 degrees Celsius can destabilize the lipid shells of the micro-capsules, causing them to release the HA prematurely inside the bottle. If the serum is visibly more liquid than usual with fewer or no visible particles, the capsule structure may have degraded. A serum with damaged capsules still contains HA and PDRN but loses the encapsulated delivery advantage - it functions more like a standard dissolved HA serum at that point. Store the serum at room temperature, away from direct sunlight and heat sources.

  • Slightly damp skin is preferable. Hyaluronic acid draws moisture from available sources, so applying it while the skin still has some post-cleanse dampness gives the HA something to draw in and lock. Applying HA serum on completely dry skin in a low-humidity environment can sometimes cause it to pull from the skin's own deeper layers instead, which may leave skin feeling drier. Pat dry with a towel after cleansing to leave a light residual dampness, then apply the serum.

  • Two to three drops is sufficient for a full-face application. More than 3 drops does not significantly increase the hydration benefit and uses up the bottle faster. Dispense into your palm, gently press the drops together to break some capsules, then press across the face starting at the cheeks and working outward. Pressing rather than rubbing preserves more capsules to burst on the skin rather than in your palm.

  • Yes, PDRN (polydeoxyribonucleotide) is typically derived from salmon sperm DNA. If you have fish allergies or follow a diet or lifestyle that avoids fish-derived ingredients, this is relevant to know before using the product. PDRN-containing skincare products are common in the Korean skincare market for their barrier-repair properties and the ingredient is generally considered safe for topical application even in individuals with fish allergies, but checking with a dermatologist is advisable if you have a confirmed fish allergy.

  • The Capsule 100 Serum Mask Sheet is designed for use 1-3 times per week as an intensive hydration boost rather than as a daily step. Using it alongside the daily liquid serum creates a routine where the serum maintains baseline hydration every day and the mask provides concentrated treatment sessions. After the mask, you do not need to apply the liquid serum as well - the mask already delivers a full serum-volume dose of the formula.

  • Hyaluronic acid is generally considered safe for topical use during pregnancy. PDRN in topical cosmetic concentrations is also generally regarded as low-risk for surface use, as it does not penetrate to systemic levels. However, skincare safety during pregnancy is a medical question rather than a cosmetic one, and the appropriate guidance is to consult your OB-GYN or midwife with the full ingredient list before use. Skinsli cannot provide medical advice on pregnancy-safe skincare.